Definition
Ivermectin is a medicine that comes in the form of a tablet taken orally and is prescribed for the combat of parasites working against the health of the human body with the structure of C48H74O14.
The structure of Ivermectin
C48H74O14
History of Ivermectin
It was the year 1970 when two scientists, Omura, and William Campbell, found a soil bacteria; based on these findings, a bacterium was invented, and both scientists named it avermectin. Later, which is a synthetic derivation of ivermectin, it was called Ivermectin and had the same structure as macrolide antibiotics.
Initially, it was used in veterinary and pets; these meds used for humans started later. Onchocera volvulus was the first disease that was first used after the year 1981. Ivermectin was one of its kind medicines when it was discovered, which is why it is one of the most important milestones in human medical invention.
Primary Use of Ivermectin
The medicine was discovered that could kill parasite worms, hookworms, and whipworms with the bacteria and viruses in the human body. There are millions of bacteria, viruses, and other parasites that live in the human body, and they help the system be healthy and work properly. But some of the bacteria and viruses enter or develop in the body that work against the human system, and rather than helping, they start destroying body cells and disturb overall health through various infections.
So, with the primary use to fight parasite worms, the med is used in the treatment of Cutaneous Larva Migrans, Ascariasis, Filariasis, Elephantiasis, Strongyloidiasis, Onchocerciasis, River Blindness, Scabies, and others. It is known to do its job with perfection, and it has been proved through various clinical surveys and trials over the years.
With the supremely effective medicine, the user must remember that this medicine falls underused with prescription only, meaning it will not be available over the counter. You can upload your authorized prescription to an authentic online pharmacy to buy this med.
How Ivermectin may combat the virus?
Its work to treat worms is as unique as the med is. It works like a soldier fights in a war; it treats by doing two significant things in the body:
Polarises worms:
This wonder medicine first polarises worms; this way, the strength of the worm decreases, and it becomes easier to fight them. Polarised worms can’t resist the med and its effects.
Paralyzing and killing worms:
After polarising worms further, ivermectin paralyzes them, so the worms are no longer able to move or multiply themselves. The next step of the med is to kill them; by killing them, they are destroyed, and the system brings them out or dissolves them through various ways.
Recommended Dosages for the Treatment of Parasitic Worms in Humans
Ivermectin 12 mg is one of the many dosages, and you will be recommended according to your needs. The recommendation will be based on a physical examination and a few tests that your health provider will make a patient do. As a patient, one needs to understand the importance of the set dosage and must obey it blindly.
Recommended dosage
This is a medicine dosage that is considered on the patient’s condition, meaning the infection, its place, stage, other than, age, weight, allergies, and other diseases, if any. Generally, 150 micrograms per 1 kilogram of human weight is the measure for dosage based on which health providers calculate a patient’s dosage.
Recommended dosage duration
Every six months, the dosage will be revised; if the patient is recovering, the dosage will be continued, and if the situation is otherwise, the dosage will be changed after a thorough examination of the patient. The change cycle in the treatment has a brief interval every three months.
What are the potential benefits and risks of using Ivermectin off-label?
Using any medicine off-label always has more risks attached to it than benefits; a medicine like this has the exact nature and tendency.
To understand this topic, one has to first know what off-label use is: Off-label refers to using the medicine without a prescription or, to say, without a health provider’s concern or guidance.
This medicine is in official practice for parasite worm control, and its use is approved by the FDA. Using it for this purpose off-label has a 100% chance of harming the patient, and the simple reason is that the patient doesn’t know his health conditions. The use of this med, it could bring severe side effects, and it could create a danger to life as well.
The other off-label use of Ivermectin that has been seen lately is in the period of COVID-19; there were some rumors that this med can be used to control COVID-19 symptoms. People have started using it, and instead of recovery or benefits, they have had multiple side effects and worsened Covid conditions. Lately, Ivermectin Australia has lifted the ban on this medication on the condition that it is not used for COVID-19 treatment. The FDA never approved this med for COVID-19 use, which was ignored.
How does Ivermectin compare to other treatments and medicines for parasitic worms?
Ivermectin, compared to other treatments, wins by a great margin.
- Ivermectin is used for multiple diseases, including Cutaneous Larva Migrans, Ascariasis, Filariasis, Elephantiasis, Strongyloidiasis, Onchocerciasis, River Blindness, Scabies, and others.
- Ivermectin is available in lower-cost generic form
- An online survey gave Ivermectin 80% positive ratings and 20% negative reviews
- The most compelling difference is the price compared to other medicines and their treatments; Ivermectin has quite a lower price
- This med has a longer half-life than other medicines; it has 16 hours of half-life
- When it comes to interactions, this med has interaction with only 94 medicines compared to its counterparts that have interaction with more than 300 other medicine
- This is the most senior medicine in this category, as it was approved in the late 20th century, in the year 1996.
Conclusion
Health providers and patients were both blessed with Ivermectin in the late 70s and early 80s to fight against various sorts of parasite worms. This med has none to fewer side effects in comparison to its other counterparts, which is a plus for the patients.
The best advice that health providers and health departments give is not to use it off-label, and with that, do not use it for any disease other than parasite worms infection, especially for COVID-19.